Yeditepe J Dent. 2017; 13(3): 15-24 | DOI: 10.5505/yeditepe.2017.91300

Hiperlipidemi ve periodontitis arasýnda bir iliþki var mý?

H. Selin Yýldýrým¹, Gülin Tulu Katý², Ömer Birkan Aðralý¹, Ülkü Noyan², Leyla Kuru¹, Bahar Kuru^3
1Marmara Üniversitesi, Diþ Hekimliði Fakültesi, Periodontoloji Ana Bilim Dalý, Ýstanbul, Türkiye.
²Özel Muaynehanede Periodontolog, Ýstanbul, Türkiye.
³Yeditepe Üniversitesi, Diþ Hekimliði Fakültesi, Periodontoloji Ana Bilim Dalý, Ýstanbul, Türkiye.

GÝRÝÞ ve AMAÇ: Bu çalýþmanýn amacý, hiperlipidemi ve periodontal hastalýk arasýndaki herhangi bir iliþki olup olmadýðýný araþtýrmaktýr.
YÖNTEM ve GEREÇLER: Bu kesitsel çalýþmada toplam 160 kiþi metabolik durumlarýna göre hiperlipidemik grup (n = 97) ve normolipidemik grup (n = 63) olarak iki gruba ayrýldý. Plak indeksi, gingival indeksi, sondalamada kanama (SK), sondalama derinliði (SD), klinik ataþman seviyesi (KAS) ve CPITN skorlarý ölçüldü. Rutin yapýlan sistemik incelemelerden trigliserid (TG), total kolestrol (TK), low density lipoprotein-cholesterol (LDL-C) ve high density lipoprotein-cholesterol (HDL-C) düzeyleri belirlendi. Günlük fýrçalama alýþkanlýklarý, arayüz temizliði, beslenme alýþkanlýklarý, alkol tüketimi ve fiziksel aktivite de anket formuna kaydedildi.
BULGULAR: Hiperlipidemik grubun ortalama SK (%), SD, KAS, CPITN skorlarý normolipidemik gruba göre daha yüksek bulundu (p<0,05). TG; TK, LDL-C, KAS ile pozitif ve HDL-C, CPITN ile negatif iliþki gösterdi (p<0,05). TK ve TG, LDL-C, HDL-C, SK, SD, KAS, BMI arasýnda pozitif korelasyonlar tespit edildi (p<0,05). LDL-C ile SD, KAS arasýnda pozitif korelasyon saptandý (p<0,05). Tüm periodontal parametreler arasýnda pozitif korelasyonlar tespit edildi.
TARTIÞMA ve SONUÇ: Bulgularýmýz, hiperlipidemili hastalarýn, normolipidemik hastalara kýyasla daha yüksek periodontal parametre deðerlerine sahip olduðunu ve periodontal hastalýða daha yatkýn olduklarýný ortaya koymaktadýr.

Anahtar Kelimeler: HDL kolesterol, hiperlipidemi, LDL kolesterol, periodontal hastalýk, trigliserid

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Is there a relationship between hyperlipidemia and periodontitis?

H. Selin Yýldýrým¹, Gülin Tulu Katý², Ömer Birkan Aðralý¹, Ülkü Noyan², Leyla Kuru¹, Bahar Kuru^3
1Department of Periodontology, Faculty of Dentistry, Marmara University, Istanbul
²Periodontist in Private Practice, Istanbul.
³Yeditepe University, Faculty of Dentistry, Department of Periodontology, Istanbul

INTRODUCTION: The aim of present study is to investigate any relationship between hyperlipidemia and periodontal disease.
METHODS: In this cross sectional study, a total of 160 individuals were divided into two groups based on their metabolic status: hyperlipidemic group (n= 97) and normolipidemic group (n= 63). Plaque index, gingival index, bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL) and CPITN scores were measured. Triglyceride (TG), total cholesterol (TC), low density lipoprotein- cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) levels had been determined during previously routine systemic examinations. Daily brushing habits, interdental cleaning, dietary habits, alcohol consumption and physical activity were also recorded.
RESULTS: The mean BOP (%), PD, CAL, CPITN scores of the hyperlipidemic group were higher than the normolipidemic group (P< 0.05). TG showed positive association with TC, LDL-C, CAL, and negative association with HDL-C, CPITN (P< 0.05). Positive correlations were detected between TC and TG, LDL-C, HDL-C, BOP, PD, CAL, BMI (P< 0.05). LDL-C was positively correlated with PD, CAL (P< 0.05). Positive correlations were detected among all periodontal parameters as expected.
DISCUSSION AND CONCLUSION: Our findings suggest that patients with hyperlipidemia manifested higher values of periodontal parameters compared to normalipidemic individuals and are more prone to periodontal disease.

Keywords: HDL cholesterol, hyperlipidemia, LDL cholesterol, periodontal disease, triglyceride.

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